Clinical studies on the effectiveness of the combination of Diosmin and Hesperidin have focused on its efficacy in venous diseases, hemorrhoids, inflammatory diseases, etc. The following is a detailed analysis:
Treatment of venous diseases and hemorrhoids
Improvement of venous function: the combination of Diosmin and Hesperidin has shown remarkable efficacy in the treatment of chronic venous insufficiency, reducing symptoms such as heavy legs, pain, morning soreness and discomfort, and improving the quality of life of patients.
Hemorrhoids: The combination can also be used in the treatment of hemorrhoids, reducing the acute symptoms of hemorrhoids, such as perianal swelling, pain, itching and blood in the stool, as well as reducing the frequency and duration of their attacks.
Inflammatory disease protection
Anti-inflammatory effect: Studies have shown that the combination of Diosmin and Hesperidin has a significant protective effect against inflammatory diseases. Mechanisms may include inhibition of arachidonoid synthesis, antioxidant and free radical scavenger effects.
CLINICAL APPLICATION: This combination showed potent anti-edematous activity in the treatment of murine chronic granulomas and was able to reduce prostaglandin synthesis in inflammatory granulomas.
Microcirculation and Lymphatic Return Improvement
Improvement of microcirculation: The combination of Diosmin and Hesperidin can improve capillary permeability and microcirculation, increase the oxygen supply and nutrient delivery to tissues, and help to promote the repair and restoration of function of damaged tissues.
Promote lymphatic reflux: This combined preparation can also stimulate the function of the lymphatic system, increase the reflux of lymphatic fluid, and reduce the accumulation of interstitial fluid in the tissues, thus relieving the symptoms of edema.