Overview
Rhodiola (Rhodiola rosea) is a plant that grows in cold parts of Europe and Asia. The root has a long history of use in traditional medicine.
Rhodiola is considered an adaptogen. Adaptogens are a class of natural substances that are believed to stimulate the body’s resistance to physical, environmental, and emotional stressors. Rhodiola extract might help protect cells from damage and regulate heartbeat.
People use rhodiola for fatigue, anxiety, depression, stress, and many other conditions, but there is no good scientific evidence to support any of these uses.
Side Effects
When taken by mouth: Rhodiola is possibly safe when taken for 6-12 weeks. Rhodiola might cause dizziness, dry mouth, or excessive saliva. There isn’t enough reliable information to know if rhodiola is safe to use long-term.
Special Precautions and Warnings
When taken by mouth: Rhodiola is possibly safe when taken for 6-12 weeks. Rhodiola might cause dizziness, dry mouth, or excessive saliva. There isn’t enough reliable information to know if rhodiola is safe to use long-term. Pregnancy and breast-feeding: There isn’t enough reliable information to know if rhodiola is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.
Autoimmune diseases: Rhodiola might stimulate the immune system. This might worsen autoimmune diseases, such as multiple sclerosis (MS), rheumatoid arthritis (RA), and others.
Interactions
Moderate Interaction
Be cautious with this combination
Medications for diabetes (Antidiabetes drugs) interacts with RHODIOLA
Rhodiola might lower blood sugar levels. Taking rhodiola along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Medications for high blood pressure (Antihypertensive drugs) interacts with RHODIOLA
Rhodiola might lower blood pressure. Taking rhodiola along with medications that lower blood pressure might cause blood pressure to go too low. Monitor your blood pressure closely.
Medications that decrease the immune system (Immunosuppressants) interacts with RHODIOLA
Rhodiola can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking rhodiola along with these medications might decrease the effects of these medications.
Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with RHODIOLA
Some medications are moved in and out of cells by pumps. Rhodiola might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Losartan (Cozaar) interacts with RHODIOLA
Rhodiola might change how the body breaks down losartan. Taking rhodiola along with losartan might increase the effects and side effects of losartan.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with RHODIOLA
Some medications are changed and broken down by the liver. Rhodiola might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with RHODIOLA
Some medications are changed and broken down by the liver. Rhodiola might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with RHODIOLA
Some medications are changed and broken down by the liver. Rhodiola might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Minor Interaction
Be watchful with this combination