{"id":1787,"date":"2025-01-10T10:00:00","date_gmt":"2025-01-10T02:00:00","guid":{"rendered":"https:\/\/diosmin-hesperidin.com\/?p=1787"},"modified":"2025-01-02T15:21:11","modified_gmt":"2025-01-02T07:21:11","slug":"introduction-of-luteolin","status":"publish","type":"post","link":"https:\/\/diosmin-hesperidin.com\/?p=1787","title":{"rendered":"Introduction of Luteolin"},"content":{"rendered":"\n<p>Luteolin (Luteolin) is a flavonoid compound, the following is a detailed description of it:<\/p>\n\n\n\n<p>1. Basic information<\/p>\n\n\n\n<p>Alias: 3&#8242;,4&#8242;,5.7-tetrahydroxyflavone; yellow flavonoids; yellow show spirit; tablets; luteolin; mignonette grass; Mistletoe tablets, etc.<\/p>\n\n\n\n<p>English name: Luteolin; Antioxidant and anti-inflammatory; cyanidenon; weldlake; Daphneflavonol; Digitoflavone; Cyanidenon 1470; Flavopurpol, etc.<\/p>\n\n\n\n<p>Chemical formula: C15H10O6<\/p>\n\n\n\n<p>Molecular weight: 286.23 (or 286.24)<\/p>\n\n\n\n<p>CAS No.: 491-70-3<\/p>\n\n\n\n<p>Density: about 1.654g\/cm3 (or 1.7\u00b10.1g\/cm3)<\/p>\n\n\n\n<p>Melting point: 330\u00b0C (decomposes at 328~330\u00b0C)<\/p>\n\n\n\n<p>Boiling point: 616.1\u00b0C at 760 mmHg<\/p>\n\n\n\n<p>Flash point: 239.5\u00b0C<\/p>\n\n\n\n<p>2. Natural source<\/p>\n\n\n\n<p>Luteolin is widely distributed in nature and was originally isolated from the leaves, stems and branches of the herb Luteolin in the genus Luteolin, family Luteaceae. In addition, it can also be isolated from a variety of natural herbs, vegetables and fruits, such as honeysuckle, chrysanthemum, bramble, white hairy sumac, artichoke, perilla, scutellaria, and nudibranch, and Brussels sprouts, cabbage, cauliflower, beets, cabbage, carrots, celery, bell peppers, peppers, peanuts, and other vegetables and fruits. Others such as olive oil, red wine, wild fenugreek, thyme grass, and sinew grass also contain Luteolin.<\/p>\n\n\n\n<p>3. Physical and chemical properties<\/p>\n\n\n\n<p>Physical properties: yellow needle-like crystals, slightly soluble in water, with weak acidity, soluble in alkaline solution, stable under normal conditions. Soluble in ethanol, ether; slightly soluble in hot water, insoluble in cold water. Aqueous solution is pleasing light yellow, soluble in 10% sodium hydroxide aqueous solution, and was dark yellow; dissolved in concentrated sulfuric acid to generate zinc salt, was dark reddish yellow.<\/p>\n\n\n\n<p>Electrochemical properties: Luteolin molecules due to the presence of phenolic hydroxyl group, so its aqueous solution shows weak acidity. Luteolin can generate colorful complexes with iron, magnesium, calcium, copper, aluminum, zirconium and other metal ions.<\/p>\n\n\n\n<p>4. Pharmacological activity<\/p>\n\n\n\n<p>Antioxidant: Luteolin is a natural antioxidant that can eliminate free radicals and prevent cell damage.<\/p>\n\n\n\n<p>Anti-inflammatory: Luteolin can regulate a variety of inflammatory mediators and change various signaling pathways involved in inflammation. It inhibits macrophage phosphorylation, inhibits nuclear factor-\u03baB (NF-\u03baB) activity, and inhibits lipopolysaccharide-induced macrophage production of inflammatory factors such as interleukin-6 (IL-6) and tumor necrosis factor-\u03b1 (TNF-\u03b1). In addition, Luteolin can also increase gamma interferon, reduce specific immunoglobulin E, and reduce the infiltration of eosinophils.<\/p>\n\n\n\n<p>Antibacterial, antiviral: Luteolin has inhibitory effect on many kinds of bacteria and viruses, such as staphylococcus, bacillus subtilis, bacillus catarrhalis, Candida albicans, Aspergillus, as well as the SARS virus, HIV virus and so on.<\/p>\n\n\n\n<p>Lowering uric acid: Luteolin has the effect of inhibiting uric acid production and promoting uric acid excretion.<\/p>\n\n\n\n<p>Others: Luteolin also has pharmacological activities such as lipid-lowering, cholesterol-lowering, antidiabetic, chemoprevention, cardioprotection and neuroprotection.<\/p>\n\n\n\n<p>5. Application fields<\/p>\n\n\n\n<p>Drugs: Clinical mainly used for cough, expectorant, anti-inflammatory, lower uric acid, treatment of cardiovascular disease and amyotrophic lateral sclerosis, SARS, hepatitis and other diseases.<\/p>\n\n\n\n<p>Food preservation: Luteolin and its derivatives can be used as food preservatives, such as prolonging the shelf life of moon cakes, peach crisp, inhibit the deterioration of food containing oil and grease.<\/p>\n\n\n\n<p>Functional food: Luteolin can be encapsulated for the development of functional food, with its main ingredient products have to reduce the intestinal and brain barrier damage and inhibit oxidative stress and inflammation and other effects.<\/p>\n\n\n\n<p>Sunscreen products: Luteolin is a natural antioxidant that absorbs UV rays and prevents cell damage, a valuable property for sunscreen products. Its derivatives are expected to be used in sunscreen products as UV absorbers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Luteolin (Luteolin) is a flavonoid compound, the following is a detailed description of it: 1. Basic information Alias: 3&#8242;,4&#8242;,5.7-tetrahydroxyflavone; yellow flavonoids; yellow show spirit; tablets; luteolin; mignonette grass; Mistletoe tablets, etc. English name: Luteolin; Antioxidant and anti-inflammatory; cyanidenon; weldlake; Daphneflavonol; Digitoflavone; Cyanidenon 1470; Flavopurpol, etc. Chemical formula: C15H10O6 Molecular weight: 286.23 (or 286.24) CAS No.: [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1788,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1787","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1787"}],"version-history":[{"count":3,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1787\/revisions"}],"predecessor-version":[{"id":1791,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1787\/revisions\/1791"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/media\/1788"}],"wp:attachment":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1787"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1787"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}