{"id":1663,"date":"2024-06-26T10:00:00","date_gmt":"2024-06-26T02:00:00","guid":{"rendered":"https:\/\/diosmin-hesperidin.com\/?p=1663"},"modified":"2024-07-25T10:18:54","modified_gmt":"2024-07-25T02:18:54","slug":"naringin-pharmacological-effects%ef%bc%8capplications%ef%bc%8ctherapeutic-effect","status":"publish","type":"post","link":"https:\/\/diosmin-hesperidin.com\/?p=1663","title":{"rendered":"Naringin-Pharmacological effects\uff0cApplications\uff0cTherapeutic effect"},"content":{"rendered":"\n<p>Naringin is mainly found in the fruit of grapefruit (Citrus grandis), grapefruit (Citrus paradisi), tangerine, orange rind and pulp, is a yellowish powder or off-white powder. Naringin belongs to dihydroflavonoids, in alkaline conditions, the pyranone ring split, by hydrogenation, can be prepared dihydrochalcone sweetener.<\/p>\n\n\n\n<p>Pharmacological effects<\/p>\n\n\n\n<p>Naringin has anti-inflammatory, anti-viral, anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, hypotensive activity, can lower blood cholesterol, reduce the formation of thrombus, improve the local microcirculation and nutrient supply, can be used in the production of prevention and treatment of cardiovascular and cerebrovascular diseases.<\/p>\n\n\n\n<p>Applications<\/p>\n\n\n\n<p>(1) Antibacterial: weaker than its glycosides on Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus.<\/p>\n\n\n\n<p>(2) Anti-inflammatory: mice intraperitoneal injection of 100mg\/kg, can reduce metritis foot and ankle swelling. Subcutaneous injection of 100mg\/kg in rats also has significant anti-inflammatory effect, which is related to the reduction of capillary permeability.<\/p>\n\n\n\n<p>(3) Anti-virus: 200\u03bcg\/ml concentration has strong inhibitory effect on herpetic stomatitis virus. It has a protective effect against viral infection in mice, and the survival time of the administered group is significantly longer than that of the control group.<\/p>\n\n\n\n<p>(4) Inhibition of ocular aldose reductase: In rats, the inhibitory effect of 10-4 mol\/L concentration of the melt was 80%. This effect may be useful in the treatment of diabetic cataract.<\/p>\n\n\n\n<p>(5) As a bittering agent: its bitterness is equivalent to 1\/5 of the bitterness of quinine (cinchona alkaloids), but yuzu (glucoside) with 7-rutinose is not bitter. Grapefruit and lime bitterness is the result of containing this product. In addition, there are anti-peroxide effect. It is also one of the flavonoids in the genus Citrus that can stimulate the blue phoenix butterfly (Pupilio protenor) to lay eggs.<\/p>\n\n\n\n<p>(6) Can be used as a raw material for the synthesis of neohesperidin and neohesperidin dihydrochalcone. Under alkaline conditions, the pyranone ring cracking, by hydrogenation, can be prepared dihydrochalcone sweetener.<\/p>\n\n\n\n<p>(7) When applied in small quantities, it can cause swelling of the perineum, stimulate the spinal erectile center and cause hypersexual function.<\/p>\n\n\n\n<p>Therapeutic effect<\/p>\n\n\n\n<p>(1)Antibacterial, antiviral<br>Naringenin and hesperidin can inhibit the growth of Staphylococcus aureus, Escherichia coli, dysentery bacillus and typhoid bacillus in the test tube, naringenin has inhibitory effect on yeast and fungi, etc., and it has preventive and protective effect on virus-infected mice. Naringin and hesperidin in grapefruit are similar to other flavonoids, with anti-inflammatory effects.<\/p>\n\n\n\n<p>(2) Reduce blood sugar<br>In the fresh grapefruit juice, contains insulin-like components, can reduce blood sugar, for diabetes, obesity patients with dietary therapy.<\/p>\n\n\n\n<p>(3) Antispasmodic and enhance the role of vitamin C<br>Naringenin contained in grapefruit has a significant antispasmodic effect. And naringenin and hesperidin in mice due to lack of vitamin C caused by intravascular blood cell coagulation in the conjunctiva of the eye and capillary resistance to reduce the role of improvement.<\/p>\n\n\n\n<p>(4)Expectorant and cough<br>The outer peel of grapefruit, that is, the commonly used Chinese medicine orange red. Containing limonene and paiene, after inhalation, can make respiratory secretions become more thin, conducive to phlegm discharge, has a good expectorant and cough suppressant effect, is the treatment of chronic cough and asthma and cold phlegm asthma in the elderly good product.<\/p>\n\n\n\n<p>The above information is for reference only, if necessary, it is recommended to consult a professional doctor or pharmacist.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Naringin is mainly found in the fruit of grapefruit (Citrus grandis), grapefruit (Citrus paradisi), tangerine, orange rind and pulp, is a yellowish powder or off-white powder. Naringin belongs to dihydroflavonoids, in alkaline conditions, the pyranone ring split, by hydrogenation, can be prepared dihydrochalcone sweetener. Pharmacological effects Naringin has anti-inflammatory, anti-viral, anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1682,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1663","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1663","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1663"}],"version-history":[{"count":1,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1663\/revisions"}],"predecessor-version":[{"id":1664,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/posts\/1663\/revisions\/1664"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=\/wp\/v2\/media\/1682"}],"wp:attachment":[{"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1663"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1663"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/diosmin-hesperidin.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1663"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}